CLOMID TREATMENT FOR INFERTILITY 

Clomid for Men – How it Works

Clomiphene is a selective estrogen receptor modulator.  It selectively binds to estrogen receptors and blocks the effects of estrogen.  This causes increased production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH).  The additional FSH acts on the Sertoli cells of the testes to stimulate sperm production (spermatogenesis).  The increased LH causes the testicles to increase the amount of testosterone being produced, which is also good for sperm production.

Clomid can help male fertility in a couple of ways.  It can help increase sperm count levels and also to correct hormonal imbalances, especially low testosterone.  By increasing a man’s sperm count, he may have a better chance of conceiving naturally or with the use of intrauterine insemination (IUI) treatment. 

Research on Clomid for Male Fertility

Testosterone production: Research has shown that low dosage clomiphene citrate treatment can help to enhance serum testosterone levels significantly and to improve the testosterone/estradiol ratio. ^[3]   

Sperm Quality and Pregnancy Rates: The American Society for Reproductive Medicine (ASRM) published a study on Clomiphene Citrate treatment’s ability to treat men with idiopathic oligozoospermia (unexplained decrease in sperm concentration or quality) and infertility.  The study separated participants into a clomiphene treatment group and a control group.  After 6 months of treatment, the clomiphene citrate treatment group participants saw a greater increase in sperm count, progressive sperm motility, and pregnancy rates than the control group.  

The treatment group experienced a 36.7% pregnancy rate, nearly three times that of the control group (13%).